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IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients

BACKGROUND: In the U.S., African Americans (AAs) present with the highest incidence and mortality rates for Colorectal Cancer (CRC). When compared to Caucasian American (CA) patients, AAs also have reduced response to the first line standard of care chemotherapeutic agent 5-Fluorouracil (5-FU). Prev...

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Detalles Bibliográficos
Autores principales: Spagnardi, Marzia, Paredes, Jenny, Zabaleta, Jovanny, Garai, Jone, Reyes, Tiana, Martello, Laura A., Williams, Jennie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754664/
https://www.ncbi.nlm.nih.gov/pubmed/36531053
http://dx.doi.org/10.3389/fonc.2022.1010380