Clipping EpCAM to release Claudin-7 for the greater good of the epithelial barrier

Maintenance of epithelial barrier function requires dynamic repair and remodeling of tight junctions. In this issue, Higashi et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202204079) demonstrate that the proteolytic cleavage of EpCAM by membrane-anchored serine proteinases releases Claudin-...

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Detalles Bibliográficos
Autores principales: Varadarajan, Saranyaraajan, Raya-Sandino, Arturo, Nusrat, Asma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754701/
https://www.ncbi.nlm.nih.gov/pubmed/36516449
http://dx.doi.org/10.1083/jcb.202211127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754701/
https://www.ncbi.nlm.nih.gov/pubmed/36516449
http://dx.doi.org/10.1083/jcb.202211127

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