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An α–π transition in S6 shapes the conformational cycle of the bacterial sodium channel NavAb
Voltage-gated sodium channels play an important role in electrical signaling in excitable cells. In response to changes in membrane potential, they cycle between nonconducting and conducting conformations. With recent advances in structural biology, structures of sodium channels have been captured i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754703/ https://www.ncbi.nlm.nih.gov/pubmed/36515966 http://dx.doi.org/10.1085/jgp.202213214 |