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An α–π transition in S6 shapes the conformational cycle of the bacterial sodium channel NavAb

Voltage-gated sodium channels play an important role in electrical signaling in excitable cells. In response to changes in membrane potential, they cycle between nonconducting and conducting conformations. With recent advances in structural biology, structures of sodium channels have been captured i...

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Detalles Bibliográficos
Autores principales: Choudhury, Koushik, Howard, Rebecca J., Delemotte, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754703/
https://www.ncbi.nlm.nih.gov/pubmed/36515966
http://dx.doi.org/10.1085/jgp.202213214