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cDC1-derived IL-27 regulates small intestinal CD4(+) T cell homeostasis in mice

The small intestinal lamina propria contains large numbers of IFNγ-producing T helper (Th1) cells that play important roles in intestinal homeostasis and host defense, but the mechanisms underlying their development remain poorly understood. Here, we demonstrate that Th1 cells accumulate in the SI-L...

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Detalles Bibliográficos
Autores principales: Ahmadi, Fatemeh, Junghus, Fredrik, Ashworth, Christian, Lappalainen, Amanda, Mörbe, Urs, Kotarsky, Knut, Agace, William W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754766/
https://www.ncbi.nlm.nih.gov/pubmed/36515659
http://dx.doi.org/10.1084/jem.20221090