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cDC1-derived IL-27 regulates small intestinal CD4(+) T cell homeostasis in mice
The small intestinal lamina propria contains large numbers of IFNγ-producing T helper (Th1) cells that play important roles in intestinal homeostasis and host defense, but the mechanisms underlying their development remain poorly understood. Here, we demonstrate that Th1 cells accumulate in the SI-L...
Autores principales: | Ahmadi, Fatemeh, Junghus, Fredrik, Ashworth, Christian, Lappalainen, Amanda, Mörbe, Urs, Kotarsky, Knut, Agace, William W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754766/ https://www.ncbi.nlm.nih.gov/pubmed/36515659 http://dx.doi.org/10.1084/jem.20221090 |
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