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The antidepressant effect of nucleus accumbens deep brain stimulation is mediated by parvalbumin-positive interneurons in the dorsal dentate gyrus

The nucleus accumbens (NAc) is a crucial region in the reward circuit and is related to anhedonia, the pivotal symptom of major depression disorder (MDD). Deep brain stimulation (DBS) of NAc has been identified as an effective treatment for severe refractory major depression; however, the underlying...

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Detalles Bibliográficos
Autores principales: Zhou, Hong, Zhu, Jiayu, Jia, Jie, Xiang, Wei, Peng, Hualing, Zhang, Yuejin, Liu, Bo, Mu, Yangling, Lu, Yisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755020/
https://www.ncbi.nlm.nih.gov/pubmed/36532368
http://dx.doi.org/10.1016/j.ynstr.2022.100492