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The antidepressant effect of nucleus accumbens deep brain stimulation is mediated by parvalbumin-positive interneurons in the dorsal dentate gyrus
The nucleus accumbens (NAc) is a crucial region in the reward circuit and is related to anhedonia, the pivotal symptom of major depression disorder (MDD). Deep brain stimulation (DBS) of NAc has been identified as an effective treatment for severe refractory major depression; however, the underlying...
Autores principales: | Zhou, Hong, Zhu, Jiayu, Jia, Jie, Xiang, Wei, Peng, Hualing, Zhang, Yuejin, Liu, Bo, Mu, Yangling, Lu, Yisheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755020/ https://www.ncbi.nlm.nih.gov/pubmed/36532368 http://dx.doi.org/10.1016/j.ynstr.2022.100492 |
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