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Acute stress impairs sensorimotor gating via the neurosteroid allopregnanolone in the prefrontal cortex
Ample evidence indicates that environmental stress impairs information processing, yet the underlying mechanisms remain partially elusive. We showed that, in several rodent models of psychopathology, the neurosteroid allopregnanolone (AP) reduces the prepulse inhibition (PPI) of the startle, a well-...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755022/ https://www.ncbi.nlm.nih.gov/pubmed/36532377 http://dx.doi.org/10.1016/j.ynstr.2022.100489 |