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Acute stress impairs sensorimotor gating via the neurosteroid allopregnanolone in the prefrontal cortex

Ample evidence indicates that environmental stress impairs information processing, yet the underlying mechanisms remain partially elusive. We showed that, in several rodent models of psychopathology, the neurosteroid allopregnanolone (AP) reduces the prepulse inhibition (PPI) of the startle, a well-...

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Detalles Bibliográficos
Autores principales: Cadeddu, Roberto, Mosher, Laura J., Nordkild, Peter, Gaikwad, Nilesh, Ratto, Gian Michele, Scheggi, Simona, Bortolato, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755022/
https://www.ncbi.nlm.nih.gov/pubmed/36532377
http://dx.doi.org/10.1016/j.ynstr.2022.100489

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