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Microglia-specific transcriptional repression of interferon-regulated genes after prolonged stress in mice

Stress-induced neuroinflammation is considered an important mechanism in the pathogenesis of depression. As immune effector cells in the brain, microglia play an essential role in neuroinflammation under stress, but the underlying mechanism remains controversial. Here, we performed RNA-seq and ATAC-...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Dong, Yuhao, Zhu, Yueyan, Sun, Daijing, Wang, Shunying, Weng, Jie, Zhu, Yue, Peng, Wenzhu, Yu, Bo, Jiang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755030/
https://www.ncbi.nlm.nih.gov/pubmed/36532375
http://dx.doi.org/10.1016/j.ynstr.2022.100495