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Microglia-specific transcriptional repression of interferon-regulated genes after prolonged stress in mice
Stress-induced neuroinflammation is considered an important mechanism in the pathogenesis of depression. As immune effector cells in the brain, microglia play an essential role in neuroinflammation under stress, but the underlying mechanism remains controversial. Here, we performed RNA-seq and ATAC-...
Autores principales: | Zhang, Yuan, Dong, Yuhao, Zhu, Yueyan, Sun, Daijing, Wang, Shunying, Weng, Jie, Zhu, Yue, Peng, Wenzhu, Yu, Bo, Jiang, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755030/ https://www.ncbi.nlm.nih.gov/pubmed/36532375 http://dx.doi.org/10.1016/j.ynstr.2022.100495 |
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