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Cell specific regulation of NaV1.7 activity and trafficking in rat nodose ganglia neurons

The voltage-gated sodium NaV1.7 channel sets the threshold for electrogenesis. Mutations in the gene encoding human NaV1.7 (SCN9A) cause painful neuropathies or pain insensitivity. In dorsal root ganglion (DRG) neurons, activity and trafficking of NaV1.7 are regulated by the auxiliary collapsin resp...

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Detalles Bibliográficos
Autores principales: Loya-López, Santiago I., Duran, Paz, Ran, Dongzhi, Calderon-Rivera, Aida, Gomez, Kimberly, Moutal, Aubin, Khanna, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755031/
https://www.ncbi.nlm.nih.gov/pubmed/36531612
http://dx.doi.org/10.1016/j.ynpai.2022.100109