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The mutational spectrum in whole exon of p53 in oral squamous cell carcinoma and its clinical implications
Mutations in p53 are common in human oral squamous cell carcinoma (OSCC). However, in previous analyses, only detection of mutant p53 protein using immunohistochemistry or mutations in some exons have been examined. Full length mutant p53 protein in many cases shows a loss of tumor suppressor functi...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755123/ https://www.ncbi.nlm.nih.gov/pubmed/36522371 http://dx.doi.org/10.1038/s41598-022-25744-8 |