The mutational spectrum in whole exon of p53 in oral squamous cell carcinoma and its clinical implications

Mutations in p53 are common in human oral squamous cell carcinoma (OSCC). However, in previous analyses, only detection of mutant p53 protein using immunohistochemistry or mutations in some exons have been examined. Full length mutant p53 protein in many cases shows a loss of tumor suppressor functi...

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Detalles Bibliográficos
Autores principales: Hyodo, Toshiki, Kuribayashi, Nobuyuki, Fukumoto, Chonji, Komiyama, Yuske, Shiraishi, Ryo, Kamimura, Ryouta, Sawatani, Yuta, Yaguchi, Erika, Hasegawa, Tomonori, Izumi, Sayaka, Wakui, Takahiro, Nakashiro, Koh-ichi, Uchida, Daisuke, Kawamata, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755123/
https://www.ncbi.nlm.nih.gov/pubmed/36522371
http://dx.doi.org/10.1038/s41598-022-25744-8

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