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Filamentous nuclear actin regulation of PML NBs during the DNA damage response is deregulated by prelamin A

Nuclear actin participates in a continuously expanding list of core processes within eukaryotic nuclei, including the maintenance of genomic integrity. In response to DNA damage, nuclear actin polymerises into filaments that are involved in the repair of damaged DNA through incompletely defined mech...

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Detalles Bibliográficos
Autores principales: Cobb, Andrew M., De Silva, Shanelle A., Hayward, Robert, Sek, Karolina, Ulferts, Svenja, Grosse, Robert, Shanahan, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755150/
https://www.ncbi.nlm.nih.gov/pubmed/36522328
http://dx.doi.org/10.1038/s41419-022-05491-4