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Glucosidase inhibitor, Nimbidiol ameliorates renal fibrosis and dysfunction in type-1 diabetes

Diabetic nephropathy is characterized by excessive accumulation of extracellular matrix (ECM) leading to renal fibrosis, progressive deterioration of renal function, and eventually to end stage renal disease. Matrix metalloproteinases (MMPs) are known to regulate synthesis and degradation of the ECM...

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Detalles Bibliográficos
Autores principales: Juin, Subir Kumar, Pushpakumar, Sathnur, Tyagi, Suresh C., Sen, Utpal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755213/
https://www.ncbi.nlm.nih.gov/pubmed/36522378
http://dx.doi.org/10.1038/s41598-022-25848-1