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Structural insights into p300 regulation and acetylation-dependent genome organisation

Histone modifications are deposited by chromatin modifying enzymes and read out by proteins that recognize the modified state. BRD4-NUT is an oncogenic fusion protein of the acetyl lysine reader BRD4 that binds to the acetylase p300 and enables formation of long-range intra- and interchromosomal int...

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Detalles Bibliográficos
Autores principales: Ibrahim, Ziad, Wang, Tao, Destaing, Olivier, Salvi, Nicola, Hoghoughi, Naghmeh, Chabert, Clovis, Rusu, Alexandra, Gao, Jinjun, Feletto, Leonardo, Reynoird, Nicolas, Schalch, Thomas, Zhao, Yingming, Blackledge, Martin, Khochbin, Saadi, Panne, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755262/
https://www.ncbi.nlm.nih.gov/pubmed/36522330
http://dx.doi.org/10.1038/s41467-022-35375-2