Cargando…

Matrix protein Tenascin-C promotes kidney fibrosis via STAT3 activation in response to tubular injury

Accumulating evidence indicates that the extracellular matrix (ECM) is not only a consequence of fibrosis, but also contributes to the progression of fibrosis, by creating a profibrotic microenvironment. Tenascin-C (TNC) is an ECM glycoprotein that contains multiple functional domains. We showed tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Qionghong, Zhang, Min, Mao, Xiaoyi, Xu, Mingyue, Liu, Shaojun, Shang, Da, Xu, Yunyu, Chen, Ruiying, Guan, Yi, Huang, Xinzhong, Zent, Roy, Pozzi, Ambra, Hao, Chuan-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755308/
https://www.ncbi.nlm.nih.gov/pubmed/36522320
http://dx.doi.org/10.1038/s41419-022-05496-z