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Matrix protein Tenascin-C promotes kidney fibrosis via STAT3 activation in response to tubular injury

Accumulating evidence indicates that the extracellular matrix (ECM) is not only a consequence of fibrosis, but also contributes to the progression of fibrosis, by creating a profibrotic microenvironment. Tenascin-C (TNC) is an ECM glycoprotein that contains multiple functional domains. We showed tha...

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Detalles Bibliográficos
Autores principales:	Xie, Qionghong, Zhang, Min, Mao, Xiaoyi, Xu, Mingyue, Liu, Shaojun, Shang, Da, Xu, Yunyu, Chen, Ruiying, Guan, Yi, Huang, Xinzhong, Zent, Roy, Pozzi, Ambra, Hao, Chuan-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755308/ https://www.ncbi.nlm.nih.gov/pubmed/36522320 http://dx.doi.org/10.1038/s41419-022-05496-z

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