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Predicting genetic interactions, cell line dependencies and drug sensitivities with variational graph auto-encoder

Large scale cancer genomics data provide crucial information about the disease and reveal points of intervention. However, systematic data have been collected in specific cell lines and their collection is laborious and costly. Hence, there is a need to develop computational models that can predict...

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Detalles Bibliográficos
Autores principales: Gervits, Asia, Sharan, Roded
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755598/
https://www.ncbi.nlm.nih.gov/pubmed/36530386
http://dx.doi.org/10.3389/fbinf.2022.1025783