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Endothelial deletion of the cytochrome P450 reductase leads to cardiac remodelling

The cytochrome P450 reductase (POR) transfers electrons to all microsomal cytochrome P450 enzymes (CYP450) thereby driving their activity. In the vascular system, the POR/CYP450 system has been linked to the production of epoxyeicosatrienoic acids (EETs) but also to the generation of reactive oxygen...

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Detalles Bibliográficos
Autores principales: Lopez, Melina, Malacarne, Pedro F., Ramanujam, Deepak P., Warwick, Timothy, Müller, Niklas, Hu, Jiong, Dewenter, Matthias, Weigert, Andreas, Günther, Stefan, Gilsbach, Ralf, Engelhardt, Stefan, Brandes, Ralf P., Rezende, Flávia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755668/
https://www.ncbi.nlm.nih.gov/pubmed/36531184
http://dx.doi.org/10.3389/fphys.2022.1056369