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Endothelial deletion of the cytochrome P450 reductase leads to cardiac remodelling
The cytochrome P450 reductase (POR) transfers electrons to all microsomal cytochrome P450 enzymes (CYP450) thereby driving their activity. In the vascular system, the POR/CYP450 system has been linked to the production of epoxyeicosatrienoic acids (EETs) but also to the generation of reactive oxygen...
Autores principales: | Lopez, Melina, Malacarne, Pedro F., Ramanujam, Deepak P., Warwick, Timothy, Müller, Niklas, Hu, Jiong, Dewenter, Matthias, Weigert, Andreas, Günther, Stefan, Gilsbach, Ralf, Engelhardt, Stefan, Brandes, Ralf P., Rezende, Flávia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755668/ https://www.ncbi.nlm.nih.gov/pubmed/36531184 http://dx.doi.org/10.3389/fphys.2022.1056369 |
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