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Evolutionary perspective of Big tau structure: 4a exon variants of MAPT

The MAPT gene encoding the microtubule-associated protein tau can generate multiple isoforms by alternative splicing giving rise to proteins which are differentially expressed in specific areas of the nervous system and at different developmental stages. Tau plays important roles in modulating micro...

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Detalles Bibliográficos
Autor principal: Fischer, Itzhak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755724/
https://www.ncbi.nlm.nih.gov/pubmed/36533137
http://dx.doi.org/10.3389/fnmol.2022.1019999