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Interferon-inducible SAMHD1 restricts viral replication through downregulation of lipid synthesis
BACKGROUND: Type I interferon (IFN) inhibits virus infection through multiple processes. Recent evidence indicates that IFN carries out its antiviral activity through readjusting of the cellular metabolism. The sterile alpha motif and histidine-aspartate domain containing protein 1 (SAMHD1), as an i...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755837/ https://www.ncbi.nlm.nih.gov/pubmed/36532074 http://dx.doi.org/10.3389/fimmu.2022.1007718 |