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Detection of somatic copy number deletion of the CDKN2A gene by quantitative multiplex PCR for clinical practice

BACKGROUND: A feasible method to detect somatic copy number deletion (SCND) of genes is still absent to date. METHODS: Interstitial base-resolution deletion/fusion coordinates for CDKN2A were extracted from published articles and our whole genome sequencing (WGS) datasets. The copy number of the CDK...

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Detalles Bibliográficos
Autores principales: Tian, Yuan, Zhou, Jing, Qiao, Juanli, Liu, Zhaojun, Gu, Liankun, Zhang, Baozhen, Lu, Youyong, Xing, Rui, Deng, Dajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755846/
https://www.ncbi.nlm.nih.gov/pubmed/36531022
http://dx.doi.org/10.3389/fonc.2022.1038380