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Enhanced proliferation of oligodendrocyte progenitor cells following retrovirus mediated Achaete-scute complex-like 1 overexpression in the postnatal cerebral cortex in vivo

The proneural transcription factor Achaete-scute complex-like 1 (Ascl1) is a major regulator of neural fate decisions, implicated both in neurogenesis and oligodendrogliogenesis. Focusing on its neurogenic activity, Ascl1 has been widely used to reprogram non-neuronal cells into induced neurons. In...

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Detalles Bibliográficos
Autores principales: Galante, Chiara, Marichal, Nicolás, Scarante, Franciele Franco, Ghayad, Litsa Maria, Shi, Youran, Schuurmans, Carol, Berninger, Benedikt, Péron, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755855/
https://www.ncbi.nlm.nih.gov/pubmed/36532282
http://dx.doi.org/10.3389/fnins.2022.919462