S1PR(4) deficiency results in reduced germinal center formation but only marginally affects antibody production

INTRODUCTION: Splenic B cells exhibit a high expression of the G protein-coupled sphingosine-1-phosphate (S1P) receptor type 4 (S1PR(4)). Little is known about the functional relevance of S1PR(4) expression on those cells. METHODS: In this study, S1PR(4)-deficient mice were used to study the role of...

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Detalles Bibliográficos
Autores principales: Riese, Janik, Hähnel, Celine, Menz, Jonas, Hannemann, Maurice, Khabipov, Aydar, Lührs, Felix, Schulze, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755867/
https://www.ncbi.nlm.nih.gov/pubmed/36532028
http://dx.doi.org/10.3389/fimmu.2022.1053490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755867/
https://www.ncbi.nlm.nih.gov/pubmed/36532028
http://dx.doi.org/10.3389/fimmu.2022.1053490

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