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Dose/exposure–response modeling in dose titration trials: Overcoming the titration paradox
Response‐based dose individualization or dose titration is a powerful approach to achieve precision dosing. Yet, titration as an individualization strategy is underused in drug development and therefore not reflected in labeling, possibly partly because of the data analysis challenges associated wit...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755917/ https://www.ncbi.nlm.nih.gov/pubmed/36125910 http://dx.doi.org/10.1002/psp4.12863 |