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MiR-378a-3p acts as a tumor suppressor in gastric cancer via directly targeting RAB31 and inhibiting the Hedgehog pathway proteins GLI1/2

OBJECTIVE: To improve the prognosis of patients with gastric cancer (GC), more effective therapeutic targets are urgently needed. Increasing evidence indicates that miRNAs are involved in the progression of various tumors, and RAS-associated protein in the brain 31 (RAB31) is upregulated and promote...

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Detalles Bibliográficos
Autores principales: Xu, Xinxin, Li, Yang, Liu, Guoxiao, Li, Kai, Chen, Peng, Gao, Yunhe, Liang, Wenquan, Xi, Hongqing, Wang, Xinxin, Wei, Bo, Li, Hongtao, Chen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755959/
https://www.ncbi.nlm.nih.gov/pubmed/36245214
http://dx.doi.org/10.20892/j.issn.2095-3941.2022.0337