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Single-Cell Analysis Reveals a CD4(+) T-cell Cluster That Correlates with PD-1 Blockade Efficacy
CD4(+) T-cell immunity helps clonal proliferation, migration, and cancer cell killing activity of CD8(+) T cells and is essential in antitumor immune responses. To identify CD4(+) T-cell clusters responsible for antitumor immunity, we simultaneously analyzed the naïve-effector state, Th polarization...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755963/ https://www.ncbi.nlm.nih.gov/pubmed/36219677 http://dx.doi.org/10.1158/0008-5472.CAN-22-0112 |