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Single-Cell Analysis Reveals a CD4(+) T-cell Cluster That Correlates with PD-1 Blockade Efficacy

CD4(+) T-cell immunity helps clonal proliferation, migration, and cancer cell killing activity of CD8(+) T cells and is essential in antitumor immune responses. To identify CD4(+) T-cell clusters responsible for antitumor immunity, we simultaneously analyzed the naïve-effector state, Th polarization...

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Detalles Bibliográficos
Autores principales:	Kagamu, Hiroshi, Yamasaki, Satoshi, Kitano, Shigehisa, Yamaguchi, Ou, Mouri, Atsuto, Shiono, Ayako, Nishihara, Fuyumi, Miura, Yu, Hashimoto, Kosuke, Imai, Hisao, Kaira, Kyoichi, Kobayashi, Kunihiko, Kanai, Yae, Shibata, Tatsuhiro, Horimoto, Katsuhisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Tumor Biology and Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755963/ https://www.ncbi.nlm.nih.gov/pubmed/36219677 http://dx.doi.org/10.1158/0008-5472.CAN-22-0112

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