The LncRNA LENOX Interacts with RAP2C to Regulate Metabolism and Promote Resistance to MAPK Inhibition in Melanoma

Tumor heterogeneity is a key feature of melanomas that hinders development of effective treatments. Aiming to overcome this, we identified LINC00518 (LENOX; lincRNA-enhancer of oxidative phosphorylation) as a melanoma-specific lncRNA expressed in all known melanoma cell states and essential for mela...

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Detalles Bibliográficos
Autores principales: Gambi, Giovanni, Mengus, Gabrielle, Davidson, Guillaume, Demesmaeker, Ewout, Cuomo, Alessandro, Bonaldi, Tiziana, Katopodi, Vicky, Malouf, Gabriel G., Leucci, Eleonora, Davidson, Irwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Molecular Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755964/
https://www.ncbi.nlm.nih.gov/pubmed/36214632
http://dx.doi.org/10.1158/0008-5472.CAN-22-0959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755964/
https://www.ncbi.nlm.nih.gov/pubmed/36214632
http://dx.doi.org/10.1158/0008-5472.CAN-22-0959

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