Activated NK cells reprogram MDSCs via NKG2D-NKG2DL and IFN-γ to modulate antitumor T-cell response after cryo-thermal therapy

BACKGROUND: Myeloid‐derived suppressor cells (MDSCs) can potently inhibit T-cell activity, promote growth and metastasis of tumor and contribute to resistance to immunotherapy. Targeting MDSCs to alleviate their protumor functions and immunosuppressive activities is intimately associated with cancer...

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Detalles Bibliográficos
Autores principales: Peng, Peng, Lou, Yue, Wang, Shicheng, Wang, Junjun, Zhang, Zelu, Du, Peishan, Zheng, Jiamin, Liu, Ping, Xu, Lisa X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756281/
https://www.ncbi.nlm.nih.gov/pubmed/36521929
http://dx.doi.org/10.1136/jitc-2022-005769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756281/
https://www.ncbi.nlm.nih.gov/pubmed/36521929
http://dx.doi.org/10.1136/jitc-2022-005769

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