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A KLK6 Activity-Based Probe Reveals a Role for KLK6 Activity in Pancreatic Cancer Cell Invasion

[Image: see text] Pancreatic cancer has the lowest survival rate of all common cancers due to late diagnosis and limited treatment options. Serine hydrolases are known to mediate cancer progression and metastasis through initiation of signaling cascades and cleavage of extracellular matrix proteins,...

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Detalles Bibliográficos
Autores principales: Zhang, Leran, Lovell, Scott, De Vita, Elena, Jagtap, Pravin Kumar Ankush, Lucy, Daniel, Goya Grocin, Andrea, Kjær, Svend, Borg, Annabel, Hennig, Janosch, Miller, Aubry K., Tate, Edward W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756341/
https://www.ncbi.nlm.nih.gov/pubmed/36413626
http://dx.doi.org/10.1021/jacs.2c07378