Cargando…
A KLK6 Activity-Based Probe Reveals a Role for KLK6 Activity in Pancreatic Cancer Cell Invasion
[Image: see text] Pancreatic cancer has the lowest survival rate of all common cancers due to late diagnosis and limited treatment options. Serine hydrolases are known to mediate cancer progression and metastasis through initiation of signaling cascades and cleavage of extracellular matrix proteins,...
Autores principales: | Zhang, Leran, Lovell, Scott, De Vita, Elena, Jagtap, Pravin Kumar Ankush, Lucy, Daniel, Goya Grocin, Andrea, Kjær, Svend, Borg, Annabel, Hennig, Janosch, Miller, Aubry K., Tate, Edward W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756341/ https://www.ncbi.nlm.nih.gov/pubmed/36413626 http://dx.doi.org/10.1021/jacs.2c07378 |
Ejemplares similares
-
Scalable synthesis and structural characterization of reversible KLK6 inhibitors
por: Baumann, Andreas, et al.
Publicado: (2022) -
Correction: Scalable synthesis and structural characterization of reversible KLK6 inhibitors
por: Baumann, Andreas, et al.
Publicado: (2022) -
A Suite
of Activity-Based Probes To Dissect the KLK
Activome in Drug-Resistant Prostate Cancer
por: Lovell, Scott, et al.
Publicado: (2021) -
Co-expression of KLK6 and KLK10 as prognostic factors for survival in pancreatic ductal adenocarcinoma
por: Rückert, F, et al.
Publicado: (2008) -
KLK6 and KLK13 predict tumor recurrence in epithelial ovarian carcinoma
por: White, N M A, et al.
Publicado: (2009)