Phosphorylation of RIPK1 serine 25 mediates IKK dependent control of extrinsic cell death in T cells

The Inhibitor of Kappa B Kinase (IKK) complex is a critical regulator of NF-κB activation. More recently, IKK has also been shown to repress RIPK1 dependent extrinsic cell death pathways by directly phosphorylating RIPK1 at serine 25. In T cells, IKK expression is essential for normal development in...

Descripción completa

Detalles Bibliográficos
Autores principales: Blanchett, Sam, Dondelinger, Yves, Barbarulo, Alessandro, Bertrand, Mathieu J. M., Seddon, Benedict
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756376/
https://www.ncbi.nlm.nih.gov/pubmed/36532075
http://dx.doi.org/10.3389/fimmu.2022.1067164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756376/
https://www.ncbi.nlm.nih.gov/pubmed/36532075
http://dx.doi.org/10.3389/fimmu.2022.1067164

Ejemplares similares