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Phosphorylation of RIPK1 serine 25 mediates IKK dependent control of extrinsic cell death in T cells

The Inhibitor of Kappa B Kinase (IKK) complex is a critical regulator of NF-κB activation. More recently, IKK has also been shown to repress RIPK1 dependent extrinsic cell death pathways by directly phosphorylating RIPK1 at serine 25. In T cells, IKK expression is essential for normal development in...

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Detalles Bibliográficos
Autores principales:	Blanchett, Sam, Dondelinger, Yves, Barbarulo, Alessandro, Bertrand, Mathieu J. M., Seddon, Benedict
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756376/ https://www.ncbi.nlm.nih.gov/pubmed/36532075 http://dx.doi.org/10.3389/fimmu.2022.1067164

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