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Low disease activity of microscopic polyangiitis in patients with anti-myosin light chain 6 antibody that disrupts actin rearrangement necessary for neutrophil extracellular trap formation

BACKGROUND: Neutrophil extracellular traps (NETs) are critically involved in microscopic polyangiitis (MPA) pathogenesis, and some patients with MPA possess anti-NET antibody (ANETA). Anti-myosin light chain 6 (MYL6) antibody is an ANETA that affects NETs. This study aimed to determine the significa...

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Detalles Bibliográficos
Autores principales: Yoshinari, Miku, Nishibata, Yuka, Masuda, Sakiko, Nakazawa, Daigo, Tomaru, Utano, Arimura, Yoshihiro, Amano, Koichi, Yuzawa, Yukio, Sada, Ken-Ei, Atsumi, Tatsuya, Dobashi, Hiroaki, Hasegawa, Hitoshi, Harigai, Masayoshi, Matsuo, Seiichi, Makino, Hirofumi, Ishizu, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756472/
https://www.ncbi.nlm.nih.gov/pubmed/36527167
http://dx.doi.org/10.1186/s13075-022-02974-9