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SPTBN1 abrogates renal clear cell carcinoma progression via glycolysis reprogramming in a GPT2-dependent manner

BACKGROUND: Renal clear cell carcinoma (ccRCC) is the most prevalent tumors worldwide. Discovering effective biomarkers is essential to monitor the prognosis and provide alternative clinical options. SPTBN1 is implicated in various cancerous processes. However, its role in ccRCC remains unelucidated...

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Detalles Bibliográficos
Autores principales: Wu, Jiajin, Miao, Chenkui, Wang, Yuhao, Wang, Songbo, Wang, Zhongyuan, Liu, Yiyang, Wang, Xiaoyi, Wang, Zengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756479/
https://www.ncbi.nlm.nih.gov/pubmed/36527113
http://dx.doi.org/10.1186/s12967-022-03805-w