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Stage-specific requirement for METTL3-dependent m(6)A modification during dental pulp stem cell differentiation
BACKGROUND: N(6)-methyladenosine (m(6)A) is the most prevalent epigenetic modification in eukaryotic messenger RNAs and plays a critical role in cell fate transition. However, it remains to be elucidated how m(6)A marks functionally impact the transcriptional cascades that orchestrate stem cell diff...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756505/ https://www.ncbi.nlm.nih.gov/pubmed/36527141 http://dx.doi.org/10.1186/s12967-022-03814-9 |