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Stage-specific requirement for METTL3-dependent m(6)A modification during dental pulp stem cell differentiation

BACKGROUND: N(6)-methyladenosine (m(6)A) is the most prevalent epigenetic modification in eukaryotic messenger RNAs and plays a critical role in cell fate transition. However, it remains to be elucidated how m(6)A marks functionally impact the transcriptional cascades that orchestrate stem cell diff...

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Detalles Bibliográficos
Autores principales: Luo, Haiyun, Liu, Wenjing, Zhou, Yachuan, Zhang, Yanli, Wu, Junrong, Wang, Ruolan, Shao, Longquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756505/
https://www.ncbi.nlm.nih.gov/pubmed/36527141
http://dx.doi.org/10.1186/s12967-022-03814-9

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