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Screening and identification of potential MERS-CoV papain-like protease (PLpro) inhibitors; Steady-state kinetic and Molecular dynamic studies

MERS-CoV belongs to the coronavirus group. Recent years have seen a rash of coronavirus epidemics. In June 2012, MERS-CoV was discovered in the Kingdom of Saudi Arabia, with 2,591 MERSA cases confirmed by lab tests by the end of August 2022 and 894 deaths at a case-fatality ratio (CFR) of 34.5% docu...

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Detalles Bibliográficos
Autores principales: Ali Dahhas, Mohammed, M. Alkahtani, Hamad, Malik, Ajamaluddin, Almehizia, Abdulrahman A, Bakheit, Ahmed H., Akber Ansar, Siddique, AlAbdulkarim, Abdullah S., S.Alrasheed, Lamees, Alsenaidy, Mohammad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756750/
https://www.ncbi.nlm.nih.gov/pubmed/36540698
http://dx.doi.org/10.1016/j.jsps.2022.12.007