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Chaperones for dancing on chromatin: Role of post-translational modifications in dynamic damage detection hand-offs during nucleotide excision repair

We highlight a recent study exploring the hand-off of UV damage to several key nucleotide excision repair (NER) proteins in the cascade: UV-DDB, XPC and TFIIH. The delicate dance of DNA repair proteins is choreographed by the dynamic hand-off of DNA damage from one recognition complex to another dam...

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Detalles Bibliográficos
Autores principales: Van Houten, Bennett, Schnable, Brittani, Kumar, Namrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756857/
https://www.ncbi.nlm.nih.gov/pubmed/33620094
http://dx.doi.org/10.1002/bies.202100011