Enhanced binding of an HU homologue under increased DNA supercoiling preserves chromosome organisation and sustains Streptomyces hyphal growth

Bacterial chromosome topology is controlled by topoisomerases and nucleoid-associated proteins (NAPs). While topoisomerases regulate DNA supercoiling, NAPs introduce bends or coat DNA upon its binding, affecting DNA loop formation. Streptomyces, hyphal, multigenomic bacteria known for producing nume...

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Detalles Bibliográficos
Autores principales: Strzałka, Agnieszka, Kois-Ostrowska, Agnieszka, Kędra, Magda, Łebkowski, Tomasz, Bieniarz, Grażyna, Szafran, Marcin J, Jakimowicz, Dagmara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756944/
https://www.ncbi.nlm.nih.gov/pubmed/36420903
http://dx.doi.org/10.1093/nar/gkac1093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756944/
https://www.ncbi.nlm.nih.gov/pubmed/36420903
http://dx.doi.org/10.1093/nar/gkac1093

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