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Enhanced binding of an HU homologue under increased DNA supercoiling preserves chromosome organisation and sustains Streptomyces hyphal growth
Bacterial chromosome topology is controlled by topoisomerases and nucleoid-associated proteins (NAPs). While topoisomerases regulate DNA supercoiling, NAPs introduce bends or coat DNA upon its binding, affecting DNA loop formation. Streptomyces, hyphal, multigenomic bacteria known for producing nume...
Autores principales: | Strzałka, Agnieszka, Kois-Ostrowska, Agnieszka, Kędra, Magda, Łebkowski, Tomasz, Bieniarz, Grażyna, Szafran, Marcin J, Jakimowicz, Dagmara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756944/ https://www.ncbi.nlm.nih.gov/pubmed/36420903 http://dx.doi.org/10.1093/nar/gkac1093 |
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