SUMO conjugation regulates the activity of the Integrator complex

RNA polymerase II (RNAPII) transcribes small nuclear RNA (snRNA) genes in close proximity to Cajal bodies, subnuclear compartments that depend on the SUMO isopeptidase USPL1 for their assembly. We show here that overexpression of USPL1 as well as of another nuclear SUMO isopeptidase, SENP6, alters s...

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Detalles Bibliográficos
Autores principales: Bragado, Laureano, Magalnik, Melina, Mammi, Pablo, Romero, Agustín, Gaioli, Nicolás, Pozzi, Berta, Srebrow, Anabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757034/
https://www.ncbi.nlm.nih.gov/pubmed/36454007
http://dx.doi.org/10.1093/nar/gkac1055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757034/
https://www.ncbi.nlm.nih.gov/pubmed/36454007
http://dx.doi.org/10.1093/nar/gkac1055

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