3D chromatin connectivity underlies replication origin efficiency in mouse embryonic stem cells

In mammalian cells, chromosomal replication starts at thousands of origins at which replisomes are assembled. Replicative stress triggers additional initiation events from ‘dormant’ origins whose genomic distribution and regulation are not well understood. In this study, we have analyzed origin acti...

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Detalles Bibliográficos
Autores principales: Jodkowska, Karolina, Pancaldi, Vera, Rigau, Maria, Almeida, Ricardo, Fernández-Justel, José M, Graña-Castro, Osvaldo, Rodríguez-Acebes, Sara, Rubio-Camarillo, Miriam, Carrillo-de Santa Pau, Enrique, Pisano, David, Al-Shahrour, Fátima, Valencia, Alfonso, Gómez, María, Méndez, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Data Resources and Analyses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757045/
https://www.ncbi.nlm.nih.gov/pubmed/36453993
http://dx.doi.org/10.1093/nar/gkac1111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757045/
https://www.ncbi.nlm.nih.gov/pubmed/36453993
http://dx.doi.org/10.1093/nar/gkac1111

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