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An RNAi screen of RNA helicases identifies eIF4A3 as a regulator of embryonic stem cell identity

RNA helicases are involved in multiple steps of RNA metabolism to direct their roles in gene expression, yet their functions in pluripotency control remain largely unexplored. Starting from an RNA interference (RNAi) screen of RNA helicases, we identified that eIF4A3, a DEAD-box (Ddx) helicase compo...

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Detalles Bibliográficos
Autores principales: Li, Dan, Yang, Jihong, Malik, Vikas, Huang, Yuting, Huang, Xin, Zhou, Hongwei, Wang, Jianlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757061/
https://www.ncbi.nlm.nih.gov/pubmed/36416264
http://dx.doi.org/10.1093/nar/gkac1084