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TERRA regulates DNA G-quadruplex formation and ATRX recruitment to chromatin

The genome consists of non-B-DNA structures such as G-quadruplexes (G4) that are involved in the regulation of genome stability and transcription. Telomeric-repeat containing RNA (TERRA) is capable of folding into G-quadruplex and interacting with chromatin remodeler ATRX. Here we show that TERRA mo...

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Detalles Bibliográficos
Autores principales: Tsai, Ru-Xuan, Fang, Kuo-Chen, Yang, Po-Cheng, Hsieh, Yu-Hung, Chiang, I-Tien, Chen, Yunfei, Lee, Hun-Goo, Lee, Jeannie T, Chu, Hsueh-Ping Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9757062/
https://www.ncbi.nlm.nih.gov/pubmed/36440760
http://dx.doi.org/10.1093/nar/gkac1114